Abstract:

Procedure of pre-operative ultrasonic imaging was conducted for nine patients with verified diagnosis of cervical adenocarcinoma. All the diagnosis were morphologically confirmed. A complex ultrasonic examination consisted of transabdominal and transvaginal echography of true pelvis organs as well as transabdominal examination of abdomen cavity and retroperitoneal space. All patients underwent true pelvis ultrasonic scanning including CDM mode, ED and Doppler pulse - wave mode. Based on the analyzed data, it was defined that echography makes it possible to determine the behavior of tumor local growth and to reveal metastases. We have traced a clear relationship of a disease stage on a ultrasonically fixed tumor size. An attempt is made to reveal specific echographic signs of adenocarcinoma of the cervix.

Abstract:

Aim: was to investigate characteristics of ultrasound image of hydatidiform mole (HM).

Materials and methods: analyzed 15 cases of this type of gestational trophoblastic tumor, which was confirmed morphologically. Transvaginal ultrasound examination was carried out in the B-mode, using the technique of color and power Doppler.

Results: it was marked out 2 ultrasound types of the tumor node in case of HM: cellular and solid-cystic. We have seen that the structure depends on the nature of the tumor vasculature.

Conclusion: determination of nodes localization and vascular lacunae in it allows to identify the danger of massive bleeding. 

References

1.     Genest D.R., Berkowitz R.S., Fisher R.A. et al. Gestational trophoblastic disease . WHO Classification of Tumours. Pathology and Genetics of Tumours of the the Breast and Femal Genital Organs / Eds. F.A.Tavassolli, P.Devilee. Lyon: IARC, 2003; 250-254.

2.     John R. Lurain, Gestational trophoblastic disease I: epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole. American Journal of Obstet. & Gynecol., 2010; 203(6): 531-539.

3.     Green C.L., Angtuaco TL, Shah HR, Parmley TH. Gestational trophoblastic disease: a spectrum of radiologic diagnosis. Radiographics. 1996; 16(6):1371-84.

4.     Kim Seung Hyup. Radiology Illustrated: Gynecologic Imaging 2nd ed. Springer-Verlag, New-York, 2012; 354.

5.     Wagner B.J., Woodward P.J., Dickey G.E. Gestational trophoblastic disease: radiologic-pathologic correlation. RadioGraphics. 1996; 16: 131-148.

6.     Mazur Michael Т., Kurman Robert J. Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach., 2nd ed.. Springer. 2005; 67-99.

7.     Stern Jeffrey L. Trophoblastic Disease. Women's Cancer information center, Web site www.cancer.org от 26/9/2012.

8.     Meshherjakova L.A. Standartnoe lechenie trofoblasticheskoj bolezni [Standart treatment of trophoblastic disease] Prakticheskaja onkologija. 2008; 9(3): 160-170 [In Russ].

9.     Meshherjakova L.A. Zlokachestvennye trofoblasticheskie opuholi: sovremennaja diagnostika, lechenie i prognoz [Malignant trophoblastic tumors: modern diagnostics, treatment and prognosis] Dis.d-ra med. nauk. M.,2005 [In Russ].

10.   Cip N.P., Vorob'eva L.V. Hirurgicheskij metod v lechenii trofoblasticheskih opuholej [Surgical method in treatment of trophoblastic tumors]. Prakticheskaja onkologija. 2008; 9 (3): 179-185 [In Russ].

11.   Tasci Y., Dilbaz S., Secilmis O. et al. Routine histopathologic analysis of product of conception following first trimester spontaneous miscarriages. J. Obstet. Gynaecol. Res. 2005; 31(6) : 579-582.

12.   Callen Peter W., Saunders W.B. Ultrasonography in obstetrics and gynecology, 1994;621.

13.   Tatarchuk T.F., Sol'skij Ja.P. Jendokrinnaja ginekologija [Endocrinological gynecology]. Kiev: Zapovgg, 2003; 244 [In Russ].

14.   Mazur Michael Т., Kurman Robert J. Diagnosis of Endometrial Biopsies and Curettings: A Practical Approach., 2nd ed.. Springer, 2005; 67-99.

15.   Zhou Q., Lei XY, Xie Q., Cardoza J.D. Sonographic and Doppler imaging in the diagnosis and treatment of gestational trophoblastic disease: a 12-year experience. J. Ultrasound Med. 2005; 24(1):15-24.

16.   Kurjak A., Chervenak A. Fran. Donald School Textbook of Ultrasound in Obstetrics & Gynecology, 3rd Edition. Jaypee Brothers Medical Publishers, 2011; 158.

17.   Chekalova M.A. Ul'trazvukovaja diagnostika zlokachestvennyh opuholej tela matki [Ultrasound diagnostics of malignant uterus tumor]: Dis.d-ra med. nauk. M., 2,1998 [In Russ]. 

Abstract:

Despite the comparatively low morbidity rate, skin melanoma is known for its high mortality rate. High metastatic potential of the tumor, urges the necessity of improving methods of diagnostics, which can identify metastasis and assess the degree of dissemination at the early stage of disease.

We have analyzed results of ultrasound imaging of one of the earliest and frequent types of progression of melanoma - metastasis in regional lymphatic nodes. The article presents results of examination of 182 patients with skin melanoma with early metastasis in lymphatic nodes, also - characteristics of the image of tumor changes are described.

The high informativeness of ultrasound research for timely identification of metastatic changes and, respectively, the increase of the rate of survival of patients with skin melanoma are demonstrated.

References

1.     American Cancer Society.: Cancer Facts and Figures 2012. [Электронный ресурс]//Atlanta, Ga: American Cancer Society, 2012. URL: http://www.cancer.org/Research/ CancerFactsFigures/CancerFactsFigures/cancer-facts-figures-2012 (дата обращения: 21.12.2012)

2.     Balch C.M., Gershenwald J.E., Soong S.J., Thompson J.F., Atkins M.B., Byrd D.R., et al. Final version of 2009 AJCC melanoma staging and classification. J. Clin. Oncol. 2009; 27(36): 6199-6206.

3.     College of American Pathologists (CAP). Protocol for the Examination of Specimens from Patients with Melanoma of the Skin [Электронный ресурс]//Version 3.2.0.0. June 2011. URL: http://www.cap.org/apps/ docs/committees/cancer/cancer_protocols/2012/ SkinMelanoma_12protocol.pdf (дата обращения: 2012.12.21)

4.     Thompson J.F, Shaw H.M. Sentinel node mapping for melanoma: results of trials and current applications. Surg. Oncol Clin. N. Am. 2007;16(1): 35-54.

5.     Ferrone C.R., Panageas K.S., Busam K. et al. Multivariate prognostic model for patients with thick cutaneous melanoma: importance of sentinel lymph node status. Ann. Surg. Oncol. 2002; 9(7): 637-645.

6.     Gershenwald J.E., Mansfield P.F., Lee J.E. et al. Role for lymphatic mapping and sentinel lymph node biopsy in patients with thick (> or = 4 mm) primary melanoma. Ann. Surg. Oncol. 2000; 7(2): 160-165.

7.     O’Brien CJ., Uren R.F, Thompson J.F. et al. Prediction of potential metastatic sites in cutaneous head and neck melanoma using lymphoscintigraphy. Am. J. Surg. 1995; 170(5): 461-466.

8.     Uren R.F. Lymphatic drainage of the skin. Ann. Surg. Oncol. 2004; 11(3 Suppl): 179-185.

9.     Blum A., Schlagenhauff B., Stroebel W. et al. Ultrasound examination of regional lymph nodes significantly improves early detection of locoregional metastases during the follow-up of patients with cutaneous melanoma. Cancer. 2000; 88 (11): 2534-2539.

10.   Voit C.A., Van Akkooi A.C.J., Sc^fer-Hesterberg G. et al. Ultrasound Morphology Criteria Predict Metastatic Disease of the Sentinel Nodes in Patients With Melanoma. J. Clin. Oncology. 2010; 28 (5): 847-852.

11.   Voit C.A., van Akkooi A.C.J., Schaefer-Hesterberg G. et al. Rotterdam criteria for sentinel node (SN) tumor burden and the accuracy of ultrasound (US)-guided fine-needle aspiration (FNAC) cytology: Can US-guided FNAC replace SN staging in patients with melanoma? J. Clin. Oncol. 2009; 27: 4994-5000.

12.   Струков А.И., Серов В.В. Патологическая анатомия. 4-е изд. М.: Медицина, 1995. 688. 

Abstract:

Case report indicates the usefulness of ultrasound for diagnostics of inorganic retroperitoneal tumor. It is necessary to use interventional methods under ultrasound control, because it gives an opportunity to clarify histological structure of tumor before surgical operation. 

References

1.     Klimenkov A.A., Gubina G.I. Neorgannye zabrjushinnye opuholi: osnovnye principy diagnostiki i hirurgicheskoj taktiki [Inorganic retroperitoneal tumor: basic diagnostic and surgical tactics]. Prakticheskaja onkologija. 2004; 4: 285-289 [In Russ].

2.     Babajan L.A. Neorgannye zabrjushinnye opuholi. Izbrannye lekcii po klinicheskoj onkologii [Inorganic retroperitoneal tumors. Elected lectures on clinical oncology] M.,2000; 420-436 [In Russ].

3.     Shhetinin V.V., Shejh Zh.V., Pachgin I.V., Kurzanceva O.O. Neorgannye mezenhimal'nye opuholi zabrjushinnogo prostranstva: osobennosti izobrazhenija i priznaki zlokachestvennosti. [Inorganic mesenchymal tumors or retroperitoneal space: features of imaging and signs of malignancy] Radiologija-praktika. 2004; 3:34-41 [In Russ].

4.     Vlasov P.V., Kotljarov P.M. Kompleksnaja luchevaja diagnostika zabrjushinnyh opuholej i opuholevidnyh sostojanij. [Complex beam diagnostics of retroperitoneal tumors and new-growth conditions.] Vestnik rentgenoogii i radiologii. 1998; 3: 30-40 [In Russ]

5.     Kilkenny J.W. IIIrd, Bland K.I., Copeland E.M. Retroperitoneal sarcoma: the Universitty Florida experience. J. Amer. Coll. Surg. 1996; 329-339.

6.     Singer S., Corson J.M., Demetri G.D., et al. Prognostic factors predictive of survival for truncal and retroperitoneal softtissue sarcoma. Ann. Surg. 1995; 185-195.

7.     Herman K., Kusy T. Retroperitoneal sarcoma - the continued for surgery and oncology. Surg. Oncol. 1998; 7(1-2): 77-81.

8.     Gvarishvili M.A. Ul'trazvukovoe issledovanie v diagnostike neorgannyh opuholej brjushnoj polosti i zabrjushinnogo prostranstva. [Ultrasound diagnostics of inorganic tumors of abdominal cavity and retroperitoneal space.] Diss. cand. med.nauk. M., 2010; 15-18. [In Russ].